Subleukemic myelosis - the benign musiyano wezvinyorwa echirwere neleukemia

Subleukemic myelosis ndeimwe boka anononoka chisingaperi neleukemia, apo mhaka chirwere inova pathological kuchinja aizotangira masero myelocyte. Panguva imwe chete havachanyatsogoni kuibvisa pamusoro hematopoietic masero ichi chirwere kwacho yakatanga reactive fibro-sclerotic maronda mapfupa marangwanda ane concomitant compression pakati mumwongo uye proliferative zvachinja chirwatata uye chiropa. Ndokusaka subleukemic myelosis anonzi myeloproliferative neleukemia.

Zvikonzero myelofibrosis uye dzakasiyana chirwere

Kazhinji, hosha rinowanikwa Varwere vari makore 50 uye vakwegura, saka mumwe ukoshi akabatanidzwa magene atadze kushanda zvakanaka zvenyukireya zvinhu hunde wokutsauka masero, autoimmune zvirwere, kutapukirwa noutachiona. Morphological substrate anova mieloza kuchinja zvose zvitatu utachiona hematopoiesis - granulocytic, megakaryocytic uye erythroid. Zviri kwokuomerwa zvinetso izvi uye zvinoenderana nokuda chirwere uye fungidziro.

Muzviitiko zvizhinji subleukemic myelosis mberi nani benign, uye pane rakananga kuwirirana pakati murwere zera nenguva kutanga chirwere uye fungidziro - muduku murwere ndiko, kuoma myelofibrosis kunoitika. Mugore chinouraya pavaipfuura chirwere, izvo zvinogona kuva pashure 5-15, uye kunyange makore 20 pashure vasabatwa vokutanga zviratidzo, varwere vanogona kwebhosvo dambudziko. Ipapo chirwere anotora pamusoro zvinhu zviri rikwanise neleukemia: vakawanda rinoparadza kuonekwa mune peripheral ropa. Zviratidzo zvakadaro Kugadzirwa chirwere vari kupisa, zviratidzo kudhaka, neta neta uye Hemorrhagic syndrome. Chinowanzoonekwa wakawedzera chirwatata uye chiropa. Mune vamwe varwere, zvichida kukurumidza kufambira mberi chirwere pamwe mangwanani pakuonekwa urwere pakati ropa uye murwere anemizatsiey.

The kunotoda mufananidzo subleukemic mieloza

Kakawanda varwere vari kunetseka akaratidza talk simba, kufundumwara mudumbu, iyo kunowedzera kufamba uye kunyanya pashure kudya (akafanirwa kune kuwedzera muna chirwatata uye chiropa). Pane kunyunyuta kuti nemusoro, kurwadziwa mapfupa uye nomuzongoza. Very kashoma, mune chirwere pavaipfuura chirwere, murwere anogona kuva zvakakomba kutsinga dzinouya vachivavhiringidza. Chiremba anofanira hazvo siya myelosis funicular - a pathological chimiro tsinga kuti kunoitika apo vamwe megaloblastic kupererwa neropa. Ichi chirwere rinowanzoberekera iri kupererwa, kunoitika muna varwere kukwana yaunodya vhitamini B12 pamuviri.

Uyezve, thrombosis zvinowanzoitika, iyo inova mhaka yakawedzera nhamba maplatelet mune peripheral ropa zvarwo, uye krovi.Poslednee coagulation zvirwere zvinogona kukonzerwa ne- morphological umbishi kunyange chaizvo vakawanda maplatelet. Nokufamba kwenguva, thrombocytosis inoenda kutanga splenomegaly, asi ari chirwatata vari kutanga nokuputsa kwete chete maplatelet asiwo masero matsvuku eropa, iro rinoita kukura kupererwa neropa.

Rinovharidzira chirongwa uye marapirwo varwere

Chirwere "subleukemic myelosis" anofanira risingashandisi kunotoda kurapwa miedzo ropa, uye migumisiro yacho sternal ponji kana iliac trepanobiopsy. Aichinja bvunzo ropa kunonyanya vasiri yakananga uye chete pamusoro kuziva kuwedzera kana kudzikisa uwandu masero eropa uye kushandura pauwandu hweavo dzavo hazvigoni chirwere "subleukemic myelosis".

Pakurapa chirwere ndiyewo novimba mamiriro mumwongo uye anowanika mapfupa mamiriro abnormalities. Mune zvimwe zviitiko, zvakakwana simba akataurwa murwere, nepo nokukurumidza mberi myelofibrosis inofanira kugadzwa mishonga zvinodhaka.

Mugore chinouraya pavaipfuura chirwere mune zvimwe zviitiko, vanofanira kumbotambudzika nemwaranzi kurapa, hombe kugadzwa mishonga kuti rikwanise myeloid chirongwa neleukemia kurapwa, nokubviswa chirwatata - asi mumwe nomumwe nyaya kurapwa chirwere murwere vanofanira kugadza anokwanisa hematologist.