"Valacyclovir": mirayiridzo kushandiswa, wongororo. Analogs "valaciclovir"

Kutapukirwa noutachiona kumirira murume pamatanho ose waro nokukurumidza upenyu. Nevamwe vavo, ivo rokuzvidzivirira hwakanaka munhu anogona kubata hwavo. Uye kukurira munhu kunoda chaiwo antivirals. Modern indasitiri ane kukura uye kugadzirwa mishonga - neindasitiri inogadzira mishonga - kwakasimbiswa uye akagadzirira kupa varwere ayo uye dzehutano mazita mishonga ivavo. Mumwe wavo ari zvinodhaka "Valacyclovir."

Nheyo kushanda ane medicament

Huru vanoshingaira fuma "valaciclovir" - valaciclovir hydrochloride (556 MG pa piritsi). valacyclovir Kwakachena - 500 MG. chikamu ichi kunoita kuti kurwadziwa kuve kwetunhu DNA nemavhairasi kukonzera herpes kuchititadzisa kuberekana pezvakaitwa (retards kana kuchititadzisa muitiro doubling DNA molecules zvachose).

Mushure medicament anopinda muviri, Unokanganisa kupinda acyclovir uye L-valine. Zvadaro, kuburikidza phosphorylation kuti acyclovir triphosphate kuumbwa iyo, chokwadi, kuchititadzisa herpes utachiona DNA usage, haritauri kuvapa (DNA) kaviri. Zvichida ichi ndechekuti acyclovir iri rapinzwa nemamiriro nemavhairasi morekuru reDNA. Tinogona kutaura kuti "Valacyclovir" riri zvikuru zvokusarudza noruremekedzo kuti munyama sei utachiwana.

Zvoupenyu simba "valaciclovir"

Kazhinji, "Valacyclovir" mirayiridzo iri yaidzorwa kushandiswa (utano nenyanzvi - kugadza kugamuchira) kuti vanhu vachitambura nezvirwere zvinotapukira ari mucous membranes uye ganda, kushatiriswa utachiona Herpeszoster. Ngativerengei kugamuchira mushonga nokuda chokudzivirira zvinangwa. Uyewo, vanachiremba vanogona kunan'anura "Valacyclovir" nokuti kudzivirirwa kubva cytomegalovirus chirwere, zvinogona kuitika paaiita ari postoperative nguva chokuita nhego transplantation. Inoshanda zvinodhaka kuda uye prolechivanii shingles.

Contraindications uye zvausingakwanisi kugamuchira

"Valacyclovir" iri contraindicated muvanhu rurefu aikanganiswa huru vanoshingaira chezvinonhuwira chezvinodhaka. Zvisingagamuchirwi mushonga kushanda panguva transplantation mu itsvo kuisirwa uye mwongo. Uyewo haana kunan'anura varwere "Valaciclovir" HIV-utachiona (kana pachiyero CD ₄ lymphocytes haringatongopfuuri mutsetse 100 MG / L). Pane contraindications pakugamuchira mushonga muvana uye kuyaruka pasi makore 18. Kunze iyi angava vana vakambova nhego kuisirwa. Vanaamai vakadaro vanobvumirwa kurapa "valaciclovir" ne makore 12.

Panyaya nezvirambidzo, sezvo "Valacyclovir" - mushonga zvikuru nehasha, pane mitemo nevakadzi vane pamuviri uye ekukurerai pamusoro kushandiswa kwayo. Chero chaiyo rabhoritari tsvakurudza nyaya iyi akanga akatakurwa kunze.

Kana mukadzi ari kuronga kuva nepamuviri uye mwana, uye mumuviri nhema wakaderera herpes utachiona, chinofanira kuziva chiremba. Nokuti mwana exacerbation kuti herpes chirwere kunogona kuva nengozi. Panguva pakuzvarwa panewo ndingangokuvara chirwere mwana kubva mai. Kodzero kuva nyaya vakaronga pamuviri rakagara rokutanga kuongororwa kuti kuvapo mumuviri rechipiri mhando herpes. Uyewo, chiremba anogona mishonga vamwe tichiita macheki ingangovapo kuziva pamusoro herpes utachiona.

Chero zvazvingava, pamberi kugadzwa mushonga ari muchikwata ichi wevarwere utano mushandi kuenzanisa zvinotarisirwa mugumisiro yokurapa nokuda raamai utano ngozi mwana ramangwana kana kare kuzvarwa. Pane ruzivo kuti acyclovir anobuda mukaka mu kuwanda kuti vari kakawanda kupfuura ayo wevasungwa munguva plasma (kubvira 0,6 kusvika 4.1 nguva).

Possible nemishonga

On kugadzirira "Valacyclovir" mirayiridzo kushandiswa sechinhu medicament dzinofunga kuti zvinogona kukonzera refu mazita nematambudziko zviitiko. Sezvo mushonga kwapfuura nemiedzo zvose kurapwa uye observational zveBhaibheri (boka varwere herpes zoster, herpes uye mumwe naye, asi achiperekedzwa immunodeficiency), zvino unowanikwa zvinenge zvose zvinogoneka nemishonga.

Human Git anogona kupindura pokushandisa medicament kusanzwa iri epigastrium. Angatanga ezvinhu akadai neanorexia, kuda kurutsa, kurutsa, manyoka, hepatitis, yakakwirira chiropa makemikari.

Pamusoro chikamu nechepakati tsinga kunogona pavakanzwa "Valacyclovir" (murefu uchapupu - uchapupu) muchimiro dzungu uye musoro, kuora mwoyo, aone zvinhu zvisipo, havachanyatsogoni kuziva (zvisinganyanyi kuitika). Kana varwere vane abnormalities mu itsvo kushanda kana zvimwe predisposing zvikonzero - zvichida kutanga pakoma. Kubva nguva nenguva unogona kunzwiwa zvakaitwa kumwoyo sezvo tachycardia (wakawedzera kwemwoyo), kana cheBP.

Kazhinji pane neutachiona zvakasikwa: kuvaviwa, mapundu, urticaria, anaphylaxis, angioedema uye angioedema. Zvimwewo mananara kunaka, pakugamuchira medicament "Valaciclovir" (analogs kunyengedza chezvematongerwe chete kana akafanana chaizvo maitiro) zvingamuka dyspnea, photosensitivity, kupera mvura mumuviri (nemvura), thrombocytopenia (ungaderedza nhamba maplatelet, iro pamwe nematambudziko kurega ropa, uye kunowedzera ropa). Uyewo, vanachiremba vanoti pamusoro zvaibvira kuratidzwa nasopharyngitis, aplastic kupererwa neropa, vasculitis.

A nzira kugamuchira uye pakupa muoti

"Valaciclovir" (Mahwendefa) akatorwa nomuromo pasina chikafu. kugamuchirwa muoti uye chipimo chemushonga zvinosiyana zvichienderana chirwere uye kwokuomerwa murwere ezvinhu.

Kakawanda, mishonga iyi nachiremba mishonga herpes utachiona. Muzviitiko izvi chamazuva dose ndiyo 1000 MG (2 mahwendefa). Zvinokurudzirwa kuti kutora mishonga maviri, rimwe piritsi mangwanani uye manheru. Drug kurapwa ingabva mazuva 5 kusvika 10 (zvakakomba weboka chirwere). In nzira iyi, uye zvakafanana dose zvinodhaka chinobviswa kuzvidzivirira nechiyero.

Shingles "Valacyclovir" mirayiridzo Chinyorwa rinokurudzira achitora yakasiyana nzira. Pano dose pamusoro 1000 MG - basa. Gamuchirai Mode - katatu pazuva (kureva mahwendefa 6 pazuva, katatu pamwe 2 zvidimbu ...). Yawapiwa kazhinji kunotora mazuva 7. Nokukurumidza pashure kutanga zviratidzo chirwere murwere kurapwa, asi kunobatsirawo zvichabviswa kubudirira nokukurumidza.

For varwere vanenge abnormalities mu itsvo kushanda zvinoda chipimo chemushonga kuchinja.

Zvimwe zviri chikumbiro "valaciclovir"

Nokuti vanhu vane itsvo kukundikana pokushandisa zvinodhaka zvinowedzera mukana wokuti nekukudziridza chetsinga yematambudziko kana zvakakomba chimiro zvirwere. Varwere vakwegura vanofanira kuva panguva yawapiwa kuwedzera mvura mvura yaunodya. Tinofanira kungwarira kuti vanhu vachitambura kubva chiropa chirwere.

Kana mishonga anogadzwa pachigaro kurapwa zvirwere zvakadai, zvakadai dzokubereka herpes, "Valacyclovir" havazokwanisi kudzivisa utachiona kuroora. Naizvozvo, panguva kosi yokurapa haafaniri zvepabonde.

Kana murwere aiva itsvo nokuisazve kana mumwongo izvozvo akaratidza kunotoda mufananidzo neHIV, pane mamiriro chakakomba immunodeficiency, kushandiswa "valaciclovir" kungaita kuti kusingarapiki, nokufa kwomunhu. Zvichida kukura thrombocytopenic purpura: Kumwe kuchinja kunotanga imwe kana kupfuura zvinoumba hemostasis, inoratidzwa melkopyatnistyh rirambe richibvira hemorrhages paganda, pasi ganda kana mucous membranes. Panewo ndingangokuvara uremic syndrome (kumira itsvo chinosara weti kumisa muitiro). Zvose izvi zvinhu (purpura uye uremia) dzakakwirira mukana kungatungamirira rufu.

Regai kugadza "Valacyclovir" vana pasi nemakore 18, sezvo pasina kurapwa ruzivo pamwe nevarwere akadaro.

Kana yawapiwa murwere hwapedyo nezvipusha, nokusagadzikana, aone zvinhu zvisipo, delirium, kuvhiringidzika - kubva kushandiswa kwezvinodhaka anofanira dzakavharwa uye kunobvunza nyanzvi.

Kudyidzana nevamwe zvinodhaka

Chero akaora zvinokosha kuratidzwa kudyidzana "valaciclovir" nezvimwe zvinodhaka haangasimbiswi. Zvisinei, chikuru vanoshingaira zvinoriumba Pfungwa iri goho nomukombiyuta itsvo kubudikidza tubular secretion. Saka, chero zvinodhaka kune imwe nzira excretion, wabatwa zvakafanana, achaita kuomesa muitiro uye kuwedzera plasma wevasungwa kuti valacyclovir. Chekutanga zvoutano vashandi vanofanira kuteerera cimetidine uye zvakafanana zvinodhaka kuti vanovhara tubular secretion mashandiro.

Kuwanda acyclovir mu yeplasma ichiwedzerwa uye apo pakugamuchira "valaciclovir" uye "Mycophenolate". Parallel kugamuchira Pharmaceuticals, complicating kana vachivhiringidza itsvo ( "Tacrolimus", "Cyclosporin" uye m. P.), Will chiwedzere mutoro pazvinhu izvi.

zvinodhaka zvakafanana

List pamusoro antiviral zvinodhaka nhasi rakafara zvakakwana. Zvangoitikawo Bumbiro ATC 4th pamwero zvinodhaka zvakawanda, asi wepedyo medicament "Valacyclovir" "Valtrex", "Vayora", "Valogard", "Valtsikon", "Valavir", "Valvira", "Vatsireks". Iyi ndaza haina chaizvo kwakakwana, zvinokwanisika kuti mberi.

The widest nevatengi kudiwa kubva analogues zvose anova nhasi "Valtrex". analoginen ichi kupinza, pamwe chete rinoita fuma. The kunyatsoshanda rekugadzirira uye kakawanda kumuvengi zviratidzo, divi siyana fanana "valaciclovir". Musiyano chiripo chete mutengo mu "Valtrex" zvikuru anodhura. Naizvozvo, varwere vakawanda vanofarira mubvunzo "Valacyclovir" kana "Valtrex" - inova nani. Mhinduro - zvose zvinodhaka zvinobatsira zvakakwana.

Opinion wevarwere uye utano nyanzvi yacho mushonga

Varwere vakawanda vanobvuma medicament nenzira yakanaka. Akaratidza refu mwero kunyatsoshanda "Valacyclovir" (wongororo vashandi zvoutano uye varwere saizvozvo) pakurapa herpes utachiona. Kuzvimba rinosvava nokukurumidza uye kwenguva zvakakwana yakareba hakuitiki zvakare. Kazhinji, pamwe mapiritsi vanhu vanoshandisa ane fuma valaciclovir mafuta (kumwe zvinodhaka kusunungurwa). Muzviitiko zvakadaro, mishonga kushanda iri nani, yakanaka mugumisiro kunoitwa nenzira pfupi nguva. Zvisinei, varwere zvinofanira kurangarirwa kuti pari zvino hakuna mushonga kuti anogona kubvisa mutumbi herpes utachiona, zvichigere yakatanga. Pane chete zvinodhaka nokuda symptomatic kurapwa.

Zvisinei, kubva yoga boka varwere vanogona kunzwa kuratidzwa nenjodzi. Kakawanda ndiye kutsaudzira iri nemudumbu: svoto, kurutsa, dyspepsia. vatengi vazhinji vari inogutswa mutengo zviduku paminiti piritsi kana mafuta "Valacyclovir." analogues Its, sezvinoita mutemo, vane zvakawanda zvinodhura, uye kubudirira chete nenjodzi zvakare zvakafanana.

Vashandi Health uyewo kuzosimbisa kubudirira ichi antiviral zvinodhaka nokuda kurapwa kwezvirwere zvakawanda zvakasikwa ichi.

"Valacyclovir" - zvinodhaka nhamba 1?

"Valaciclovir" mirayiridzo Chinyorwa Positioning sezvo zvikuru inoshanda antiviral zvinodhaka. Zvirwere zvinokonzerwa nemavhairasi mavambo kunogona kwazvo uye kukanganisa upenyu munhu zvachose. Zvisinei mushonga, ngatitii nokuda herpes chirwere asati tega. Hongu, uye chero chirwere nemavhairasi anogona kudzokera pashure imwe nguva. The mhedziso kuzvipira chinangwa uye pokushandisa "valaciclovir" pasina zano chiremba hwakazara matambudziko zvakakomba. Muduku zvinogona kutarisirwa - chiri kushayikwa yakanaka. Kana paine matambudziko akakura mumuviri chokuita kutoitwa itsvo transplantation chete itsvo uye mwongo nokuzvidzora "valaciclovir" anogona uye kunotungamirira kurufu. Uye nemishonga zvakawanda.

Kana mushonga rinofanira neMutungamiriri kupinda chiremba, uyo akatanga kugamuchirwa redunhu uye akasarudzwa chipimo chemushonga kunyatsoshanda "valaciclovir" iri kurapa chirwere ichava kunonyanyisa panguva shoma mukana wokuti rwakashata zviitiko uye zvakaoma kunzwisisa nokugamuchira medicament.