Vasodilator - chii? Description of pharmacological boka

Vasodilation ndiwo muitiro dzokuzorora pamusoro tsandanyama rukoko ari vascular rusvingo. The mushonga kuva yakafanana mashandiro chiito uye kushandiswa pakurapa mwoyo nokukundikana uye BP, akadana zvinoenderana izwi - vasodilator. Chii uye chii zvokushandisa zviri vasodilators, funga zvakare.

tsananguro

Neb cardiac goho, kukura mwoyo kukundikana, zvaanopa simba ari adrenergic huta uye renin-angiotensin hurongwa, zvichiguma kusunungurwa angiotensin II uye norepinephrine. Active zvinhu kusungira kuna receptors, iyo inosvitsa vasoconstriction.

Danho rokutanga mwoyo kukundikana kunoda mashandiro akadaro, nokuti anobvumira kuramba zvinodiwa BP. Zvisinei, kwenguva refu aienda pamusoro mutsinga zvichiita kuti pave congestive pezvakaitwa mumapapu uye kuderera cardiac goho.

Vasodilators - zvinodhaka (mazita okuremekedza anogona kuwanikwa kushandiswa mabhuku ezvokurapa uye pharmacological, uyezve, pazasi isu nyora zvikuru nevanhu achishandisa boka iri), kushandiswa kuwedzera midziyo ropa. Zvinoguma kukura hypotensive maturo. Chimwe chinokosha chiratidzo ichi mhando mushonga chikosoro kwomwoyo. Zvakadini kana mamiriro kuchabatsira vasodilators? Kugadzirira pamwoyo chikosoro kushandiswa kuwedzera coronary midziyo.

kupatsanura zvinodhaka

Zvichienderana iyo nzvimbo vascular mubhedha sei surfactants, pane mapoka matatu vasodilators:

1. arterial:
   • "Hydralazine";
   • karusiyamu mhandu.
2. venous:

• nitrates;
• sydnonimine.

Venous vasodilators

Venous vasodilator - chii? Izvi mushonga zvinokonzera ungaderedza mataurire venous vascular rusvingo. Venules sei hwakaderera kuwanda vanoshingaira zvinhu kupfuura tsinga. Muzviitiko zvakadaro, nitrates inoshandiswa kuzorora hombe mutsinga, kuwedzera muropa, achidzikisa mutoro pamwoyo, achidzikisa kudiwa myocardial okisijeni kudiwa.

Venous vasodilators - kugadzirira (mazita, mishonga inorondedzerwa tafura), izvo vanonzi zvikuru mishonga zvose antianginal. Side Marwadzo mashoma uye pfupi.

Arterial vasodilators

Arterial vasodilator - chii? Izvi pharmacological mumiririri vanoshingaira venhumbi relaxes kuti tsandanyama rinenge riri arterial rusvingo.

Somuenzaniso, "Hydralazine" - mushonga kuti anowedzera kwemwoyo, zvakawedzera ropa riyerere kuti itsvo uye uropi kuti pane dzepanguva kushaya kwakaita vascular spasm. Rakashandiswa siyana BP, chirwere cheBP dambudziko akabatana nevamwe vamiririri.

Side Inovapo "Hydralazine":

• cephalalgia;
• akatsvuka chiso;
• Chimiro edema;
• kudzikisirana Kuratidza angina;
• chirwere zvakafanana chinonzi systemic lupus erythematosus.

"Diazoxide" - mumwe vasodilator, iro rinoshandiswa kureva kuedza vane chirwere cheBP dambudziko. Nomutsinga, lowers BP pashure maminitsi 2-3. Uyezve, mumiririri rinoita kutandara simba pamusoro dumbu uye mvura chengetedzo.

Karusiyamu mhandu - boka arterial vasodilators, zvinosanganisira zvinotevera zvinoreva:

1. "Nifedipine" - inobvisa munhu spasm pakati coronary midziyo, lowers BP, akazoita basa pomwoyo.
2. "Verapamil" - kunoderedza myocardial contractility, paanodzorera mwoyo mutinhimira uye BP.

Kugadzirira Mixed Type

Mixed vasodilator - chii? Izvi zvinoreva basa chirungiso iyo Unotsigira spasm pamusoro arteries uye mutsinga. Mumwe inonyatsobudirira ndiye yavaibvisa nitroprusside. Mashandiro chiito zviri zvakafanana nitrates. Intravenous kwokubatsira mushonga kunokonzera kukurumidza uye simba chaizvoizvo, asi zviri pfupi-akararama.

Rinoshandiswa senzira vasodilator pakuparwa chakasimba uye chisingaperi mwoyo nokukundikana, vane chirwere cheBP mamiriro pamusoro pakanyorwa myocardial infarction, vane chirwere cheBP encephalopathy nezviratidzo. Pakatanga yavaibvisa nitroprusside kunogona kukonzera dzungu, nomusoro, kurasikirwa pfungwa, kuda kurutsa, tachycardia.

ACE FIs - boka zvinoreva ichivharira paumbwe angiotensin rokutendeutsa enzayemu, nokudaro haana kubereka angiotensin II. In zvakafanana, pane kusimbisa mugumisiro diuretics. Kupatsanura pakati ACE FIs hwakavakirwa kwemakemikari kwavo mamiriro:

1. Ine sulfhydryl boka:
   • "Captopril".
   • "Zefenopril".
   • "Benazepril."
2. A carboxyl boka:
   • "Lisinopril".
   • "Enalapril".
   • "Spirapril".
3. Phosphinyl boka rine:
   • "Fosinopril".

The Formulations vane zvazvakanakira kuti asymptomatic kuruboshwe ventricular dysfunction, atherosclerosis pamusoro carotid arteries, metabolic urwere, microalbuminuria, atrial fibrillation, myocardial infarction, nephropathy, non-shuga.

Children vasodilators

Vasodilators, zvinodhaka vana anoshandiswa chete kwazvo pathologies. Sezvo aiwanzoshandiswa myotropic rinoreva ( "Dibazol" "Papaverine") uye ganglionic ( "benzogeksony").

Vana vanowana vasodilators chetsinga kurapwa. Mari chinangwa tivandudze uropi kweropa, anoshandiswa mune "chena" hyperthermia uye hydrocephalus.

Chero mishonga anosarudzwa nomumwe, zvichienderana ezvinhu omurwere, kwokuomerwa kutyorwa, chimiro uye kosi yacho chirwere. Self-mishonga haina inokurudzirwa.