Adenovirus (adenovirus) - chii? How kubata adenovirus?

Kune zvirwere zvakawanda zvinogona kukonzera zvirwere zvakasiyana-siyana muvanhu. Pakati pavo kanoda inogarwa adenovirus. Imhandoi microorganism, iyo nhengo zvinokanganisawo, sei kurwisa? Vanhu vazhinji vakanzwa munhu causative mumiririri akadaro.

Adenovirus - worudzii muviri?

Utachiona ndohwaJehovha mhuri adenovirus mastadenoviruses akare. Pari zvino pane anenge makumi mana serotypes. Sechikamu nechimwe utachiona rine DNA Morekuru zvokuti kuva pachena kuchiitwa nevamwe vamiririri kufema.

Inosimbiswa kuti adenoviruses - a microorganism idenderedzwa chimiro ane dhayamita pamusoro 70-90 nm. Ane sangano nyore.

utachiona zvakatanga kure tonsils uye adenoids mwana anorwara muna 1953. Naizvozvo, kana zodzera microscopy pavarwere vane chakasimba kufema nemavhairasi chirwere vakaonawo adenovirus. Chii ichi chisinganzwisisike chirwere? Asi kunoratidzwa, uye vari varwere nezviratidzo pakati atypical nemabayo pamwe kukura conjunctivitis.

Sei zvichinzi inoparadzirwa

Utachiona nemavhairasi utachiona hwakakura angava kuenda neherikoputa uye fecal-nemumuromo nzira, vachishandisa vanorwara munhu zvinhu, zvokudya, mvura mvura rakazaruka kana nokushambira madziva. Adenovirus - chiri chirwere chinofamba sezvinoita munhu ane huripo zviratidzo, uye inotakura utachiona, hazvina zviratidzo chirwere.

Utachiona ndiyo husingakwanisi kwezvakatipoteredza kuchinja, haina kuparadzwa mhepo uye mvura zvikaramba kwenguva refu ari medicaments zvinoshandiswa kunorapwa ophthalmology.

Nzvimbo okusuma utachiwana ndivo mucous membranes ari kufema uye zvomudumbu hurongwa, ari conjunctiva. Rakapinza muruoko epithelial masero uye node nodes, rwunotanga kuwanda. Ndicho kukura CPE uye paumbwe intranuclear inclusions. The zvakakanganisa masero vaparadzwa uye kuparara, uye utachiona migrates muropa pasi, yekutapurira nedzimwe nhengo.

Pakati vamwe serotypes adenoviral vasangana oncogenic vamiririri, achiita paumbwe nyanyisa anomera kwemhuka.

Somugumisiro adenovirus chirwere epithelial rinenge kuti muduku kumwero mechidziro basa, izvo zvinoderedza masoja utachiona chinja mumuviri uye zvinogona kukonzera concomitant kukura kuparadzwa kwemabhakitiriya. Haina kuva pathogenic kukanganisa mhuka.

Kudzivirira ré-chirwere

Kazhinji varwere kupora kubva adenovirus chirwere, akakudziridza simba kutapata, asi chete kune imwe serotype adenovirus. Zvinorevei? Zvakaratidza kuti munguva nekutambira nevanhu yakananga utachiona havasi vanhu vanorwara.

Pakuzvarwa, mwana anowana kurwisa hosha, izvo haazombotaurwi pashure pemwedzi mitanhatu.

Mhando dzakasiyana-siyana adenoviral zvirwere

Kune vose anongoitika uye kupararira kuratidzwa adenoviruses, kazhinji pane chikwata chevana. Utachiona kunoratidzwa siyana kuratidzwa, sezvo utachiwana kunokanganisa kufema hurongwa, mucous membranes, maziso, ura, dundira.

Siyana anoita adenoviruses dzevanhu. zvirwere kupatsanura dzinosanganisira:

• chenjera kufema chaikonzerwa noutachiona akabatana nefivha (kazhinji ikabuda pauduku);
• chenjera kufema chaikonzerwa noutachiona vakura;
• nemavhairasi nemabayo;
• chenjera adenoviral angina (kunyanya mune vana panguva pashure kurapwa mvura yezhizha);
• pharyngoconjunctival fivhiri;
• plonchaty conjunctivitis;
• mesadenitis;
• chenjera follicular conjunctivitis;
• vakura chifo keratoconjunctivitis;
• intestinal chirwere (enteritis, nemavhairasi manyoka, gastroenteritis).

Nguva yose incubation nguva kubva matatu mapfumbamwe mazuva.

Kuwanda zvirwere

Pakati zvose zvakanyorwa zvirwere zviri kufema ezvinhu ari chikamu adenoviral kukundwa nezvokuvandudzika pakati 2 kusvika 5%. Chinonyanya aifumura vachangoberekwa nevana.

Kubva 5 kusvika 10% of nemavhairasi yezvakaita chirwere munhoroondo kuti adenovirus. Zvinorevei kuti kuratidza? Chokutanga, izvi zvinhu dzinopupurira wayo kwazvo kuparadzira, kunyanya mu pauduku (75%). Izvi, kusvikira 40% kunoitika muvana pasi 5 years, uye pauwandu hweavo asara anoparadzirwa pakati pemakore 5 uye 14 makore.

Adenoviral zvirwere kufema mutambi

Kutanga chirwere Fivha kusvika 39 ° C, kutemwa uye zvayo zvakawanda zvive. On vana zvakasiyana kuita adenovirus, zviratidzo kuonekwa zvishoma nezvishoma mune vana, ivo vaine lethargy, kushaya kudya, kuderedzwa mugiredhi muviri tembiricha.

Fever kunogara kusvika gumi mazuva. tembiricha muviri anogona zvino kuwira, ipapo agomukazve, zviratidzo matsva akanyorwa panguva ino.

Kubva pamazuva chirwere wokutanga pane nasal kuzara. Zuva rakatevera pane zvakawanda mucous kana mucopurulent zvinoerera, achiperekedzwa yakaoma chikosoro kuitika kakawanda.

Rinotanga kukuvadza huro yake nokuda akatsvuka huro, tonsils maberere, wokupedzisira kuwedzera kukura.

Zviratidzo yemweya kuzvimba

chimiro ichi ndicho, izvozvo kunoratidzwa kuzvimba ari Airways. Huru zvirwere zvinosanganisira laryngitis, rhinopharyngitis, tracheitis, bronchitis pamwe mwero General kudhaka.

Signs pharyngoconjunctival fivha

Inokanganisa pamusoro huro ane adenovirus. Zviratidzo inokonzerwa nokuwedzera kuita tembiricha kuti vhiki mbiri uye zviratidzo pharyngitis. Kazhinji pane hosha huro uye neapo uchida kukosora, utachiona asingadi kuenda mhiri kufema turakiti.

Zviratidzo conjunctivitis plonchatogo

Most vanotambura vakuru uye vana vavo vari kuyaruka. The chirwere kunokonzerwa yaitsigira divi kana bilateral conjunctivitis pamwe paumbwe firimu racho mucosa repasi fungiro. Panewo nemuumbi kuzvimba uye akatsvuka kuti zvinyama yakapoteredza ziso, marwadzo, yakawedzera vascular mubhedha ari conjunctiva uye fivha. In chirwere ichi kufema maitiro hapana infestation adenoviral chirwere.

zviratidzo tonsillopharyngitis

Hosha ikabuda vana kuenda kukireshi zera. A maitiro kuchiitwa tonsillopharyngitis vari anogumbura zvachinja jira akaita pharynx uye tonsils. Adenovirus, pikicha izvo anopiwa pazasi, chinokonzera angina.

Mhando intestinal siyana

Kuratidzwa adenovirus hweHIV vari dumbu iri chokuita kukura usinganyanyi nemavhairasi manyoka uye gastroenteritis. Utachiona hunokonzera kuda kurutsa, kurutsa, manyoka, asina tsvina, zvishomanana kuwedzera tembiricha muviri. Kuwedzera intestinal zvinetso zvichibvira noutachiona ari kufema ezvinhu Somuenzaniso, rhinopharyngitis kana laryngotracheitis.

mesenteric adenitis

Chimwe chimiro hosha, umo abdominal marwadzo uye fivha. Zvinokwanisika concomitant noutachiona kuti inoda inorwisa utachiona kurapa.

Sei kuziva causative mumiririri

Pane Nzira dzinoshandiswa iyo adenoviruses takatsunga. Zvidukuduku inoshandisa sezvo bvunzo mutsvina yadzo zvinhu zvinoerera kubva nasal ndima, huro, ziso conjunctiva. Kuti asimbise nayo utachiona inoculation rinoshandiswa riri kuitwa tsika epithelial masero dzevanhu.

Murabhoritari chirwere kushandisa immunofluorescence microscopy wanikidza maantigen pamusoro adenoviruses. Zvidukuduku ayo zvombo ane uwandu nzira kuti anogona kuona chirwere ichi. Izvi zvinosanganisira nzira kuti:

• Rác - serodiagnosis kutapukirwa noutachiona nokuda mukwanisi-antibody maitiro IgG uye IgM.
• Hai - Haemagglutination maitiro anoonekwa braking kwacho nokuda kuziva utachiwana kana antibodies muropa murwere plasma. Nzira inoshanda kuburikidza kudzivisa nemavhairasi maantigen kubva masoja serum antibodies pashure hwakaraswa mano nemavhairasi kuti agglutinate masero erythrocytic.
• Rn-nzira kunobva kuderedza cytopathic migumisiro utachiwana somugumisiro kubatana uye yakananga AT.

Kuziva nemavhairasi antigen anogona kuva pachishandiswa nokukurumidza nechirwere. Yemanyorero zvinosanganisira kutsvakurudza kwakadaro:

• Immunoassay kuongorora kana Elisa - rabhoritari nzira immunological Kutsunga Qualitative kana quantitative zvechadenga utachiona, pahwaro chaizvo maitiro pakati imwe antigen uye antibody;
• immunofluorescence maitiro, kana Rif, izvo anobvumira kuziva miedzo antibodies kuti adenovirus chirwere (kana nzira iri kushandiswa zodzera, prestained dhayi);
• Analysis radioimmunoassay, Ria kana zvinoita kuti kuyera chero wevasungwa utachiona iri mvura mvura.

How kurwisa chirwere

Pashure pokugadzwa kuongororwa zvakarurama pamberi chiremba uye murwere ndiwo mubvunzo sei kurapa adenovirus. Zvinofungidzirwa kuti mishonga chaizvo havasi parizvino dziripo.

Zvichienderana dhigirii zvinogona kuitwa pamba pamusoro chiremba wako pakurapa chirwere kana ari muchipatara. Regai zvinoda muchipatara nyoro kune mwero siyana utachiona, akanga uneventful. Muzviitiko zvakaipisisa kana matambudziko vanofanira kubatwa muchipatara pasi pokudzora chiremba.

Kuti akunde adenovirus Mabatirwo nyoro siyana ipfupi kundorara zororo. At muviri tembiricha pamusoro 38 ° C paracetamol raitongwa panguva dose pamusoro 0.2 kusvika 0,4 g 2 kana 3 kanomwe pazuva, iro unoenderana 10 kana 15 MG pa 1 kg kurema muviri pazuva. By adenoviral chirwere haana kutora acetylsalicylic acid.

Zvichienderana chimiro chirwere symptomatic kurapwa antitussive, expectorant vamiririri anogona kurapa "Stoptussinom" "glaucine," "Glauventom" "Mukaltin".

The inhalation aerosol kushandiswa deoxyribonuclease. Ndivo 2 kana 3 kanomwe pazuva kwemaminitsi 15. Rhinitis vakaroverera chaiyo mhino madonhwe.

Kusimudzira kutapata uchishandisa vhitamini zvivako pamwe fanira zviri ascorbic acid, tocopherol, rutin, thiamine uye riboflavin.

Kana akarova meso adenovirus kurapwa rinoitwa mumate deoxyribonuclease enzayemu mune 0.1- kana 0.2% mhinduro ose 2 maawa ari 3 madonhwe. Chiremba anogona mishonga kukamura uchishandisa Mabatirwo conjunctivitis glucocorticoid okuzora, interferon kugadzirira, ziso nezvizoro vane antiviral kana oxoline tebrofenom.

kudzivirira chirwere

Kuitira kudzivirira adenovirus hweHIV uye kuderedza kuitika chakasimba kufema nemavhairasi chirwere uchishandisa kubaya chete yokudzivirira mhenyu, izvo zvinosanganisira attenuated masero nemavhairasi koshesa serotype.

Yaiwanzoshandiswa zvinodhaka adenovirus mhando 4 kana 7 kuvadzivirira kubva gastrointestinal kugaya chinokosha Coated Kamudzira.

Pane dzimwe yokudzivirira vari mhenyu uye inactivated siyana, asi havana kushandiswa nokuda oncogenic basa adenoviruses.