Invisible zvatinosiita ziso Blashko mutsetse uri muviri womunhu

Imperceptible kuti akashama ziso mapatani muviri kuitika pasi pokudzora endogenous uye exogenous kunaka zvinhu. Hunodzorwa zvokurwara sezvo mitsetse Blashko. Melanogenesis akaratidza hypopigmentation, chokuita boka zvirwere dermatoses. Zvinoonekwa benign mubereko kuti sayenzi. Nzwisisa nheyo chitarisiko bundu, zvinokwanisika kudzivirira chimiro melanoma.

Nhoroondo nokudzidza zvirwere ganda

mutsvakurudzi German matambudziko dermatological vakawana Blashko mutsetse muna 1901. Dzinomirira muenzaniso pigmentation, zvakafanana mamiriro varwere vose. The chirwere ainzi pashure nezita musayendisiti, anonzi Alfred.

Dermatologist akasimbisa ukama panowanikwa zvokurwara X-okutodza. On utano ganda imperceptible kuchinja wavo wenguva yevasungwa. Somugumisiro kunyongana kwaiva kumaruwa vaitamira malanoblastov paumbwe zvinoonekwa nharaunda muenzaniso. Status masero mutated ndiyo novimba muviri huta breakdowns. Zvisinei, matambudziko dermatological anogona kuwanikwa vachiberekwa nhaka chirwere.

The zvikonzero kuti zvarakasiya ganda dzevanhu

Ziva zvinhu zvinotevera Education Blashko mutsetse uri muviri:

• Chimerism - kazhinji vachinzi mamiriro kana munhu anoona marudzi maviri DNA. A siyana akagadzirwa majini kunokonzera paumbwe pigmentation pamusoro muviri. Migumisiro izvi zvinoratidza makunakuna pamwe marudzi maviri akasiyana. VaBennett ganda zvokurwara anova Fusion kuti zai achiri padanho pamuviri.
• Human kushushikana kusaenzana - muenzaniso runobva aumbwa.
• Dzinza rako - kuchinja DNA kwevanhu. Chikonzero chakaita vachiberekwa zvokurwara anova nevi: depigmented, pigmented, sebaceous, Linear verrucous anogumbura.
• Genetic vaiitawo DNA panguva embryogenesis - masayendisiti vakatasva maumbirwo nyama dzevanhu: mune imwe keji yakatarwa majini ari kuchengetwa. Kunyange zvazvo kwakabva yokupedzisira rinobva chete zygote.

Hunhu nechitarisiko dermatosis

Zvinoodza mwoyo kuti haazivi okuti "Blashko mutsetse" - chii ichocho mutsetse? Zvinetso zvakadaro kazhinji kuwanikwa vana vachangoberekwa, hapana anopfuura 2% izvo zviri mavari chimiro pathologies. Sechivako DNA ndiyo pakutanga chine ruzivo chirwere. External zviratidzo simuka somugumisiro zvarakasiya momuviri muviri.

Blashko mutsetse dzinoratidzwa masero matatu mumuviri, kunowanika chirwere:

• Epidermal keratinocytes - vawana zvokurwara kazhinji kuchengetwa somugumisiro chimerism.
• Ruvara - iri dzapasi akaturikidzana ari Epiderme e.
• Vafambi muganhu ruvara masero - zvinotisvitsa kuchinja ruvara rweganda, nomunyika zimba Kamudzira kupinda pamusoro rukoko pamusoro dermis. mamiriro iyi pasika chokuziva hunhu paumbwe melanoma.

zvekunze zviratidzo

The mabhuku ezvokurapa anopa mashoko pamusoro pemitsara Blashko: kuti chirwere nyama yevanhu, izvo kunooneka pacharo kana yezvikanganiso mumuviri upenyu. Structure muenzaniso asingaoneki seri chikamu afanane ruvara emhuka: mbizi kana ingwe. Rinogona kuzivikanwa nokuda ultraviolet nemwaranzi.

Ruvara rweganda kwevanhu kunoenderana pafuma ruvara rwe-melanin. Zvinonzi akaumba ari Epiderme e nyama, basal rukoko unotora melanocytes. Zvarakasiya mu nedanho melanogenesis kunotungamirira kuti ruvara kuchinja nemaziso oneka:

• Hyperpigmentation - runobva muenzaniso pane rima makwapa paganda, Munokudzwa zvakajeka kubva inokosha mumvuri cover.
• Hypopigmentation - kufirwa ruvara rweganda masero, zvichiguma whitish nzvimbo. Rare zvokurwara vakachengeta asina kupfuura 1% kubva vachangoberekwa vacheche.

An kuratidzwa kwokunze chirwere muenzaniso anova V-zvakaumbwa, muchimiro curls kana Wavy mitsetse. Kazhinji kuumbwa pamusoro zvikamu izvi muviri;

• shure;
• kumativi;
• pamapendekete;
• musoro.

diagnosing dambudziko

Line richiswedera Blashko kuoneka apo munhu irradiated pamwe ultraviolet chiedza, asi upenyu kazhinji inopfuura kuzviongorora kwakadaro. Kudzidza mamiriro muviri kutanga chava mberi zvokukura chirwere. In achangoberekwa vacheche, zvivara ose hypopigmentation pamusoro muviri zvakaoma kuona. Mwana anowana ari kuchinja ganda mumakore mashoma.

On mamiriro pamakamuri sei chine okutodza. Kana zviri chaizvo yakasiyana pedyo zvikamu paganda, zvarakasiya kuchengetwa coloring micheka. Saka hypopigmentation kuonekwe zvinotevera ezvinhu:

• Ita mhirizhonga makwapa - kufarira zvesayenzi nemhaka gogonera hurongwa. Mufananidzo inoratidza kuchengetwa zvitarisiko zvakaoma muchimiro zvisungo, Chess masero.
• Vemunyika - pachena rimwe gwapa imwe nzvimbo.
• Generalized - angaperekedzwa zvirwere nhengo dzomukati.

Nei tichifanira kudzidza vanodhirowa iri paganda?

Vanachiremba vava akarwawo unaku kuongorora nzvimbo dzomuviri pane yematambudziko zvinoonekwa paganda. Pano, huru chakarurama ndiye mutsetse Blashko, maperembudzi kuongororwa kuti akarurama zvawanikwa. Izvi zvinova zvakakosha apo matambudziko anotevera dermatological:

• chimerism;
• mosaicism;
• zoster;
• nevus;
• melanoma.

Complex textures zvinokosha chete kurutivi tsvakurudzo, nokuti munhuwo zvake, zvakadai kuongorora haisati kutungamirira vamwe ndezvipi pamusoro chirwere. Masayendisiti vanoronga kuzivisa chinangwa mapatani pamusoro womunhu. Zvichida kuwanikwa kuchabatsira kubvisa migumisiro isingawanzowanikwi ganda chirwere.