Glutamic acid: chikamu chezvisikwa, kushandisa mune zvemishonga nemitambo

Iko monoamino- dicarboxylic acids inonzi glutamic uye aspartic acids. Iyi yekupedzisira yakasarudzwa muna 1868 kubva kumapuroteni emichero. Izvi zvinogadziriswa mumuviri womunhu, chikamu chemuumbi weproteine akawanda emiti nemhuka yakabva, inoshandiswa mukugadzirwa kwebiosynthesis yezvigadzirwa zve nitrogenous nucleic acids uye urea, kutamisa kweamino acid, nezvimwewo.

Glutamic acid yakatanga kurega muna 1966 kubva ku hydrolyzate yegoro gluten. Chimwe chikamu chikuru cheiamino acid inowanika mu globulins uye albumins yeropa. Glutamic acid inobatanidzwa mu decarboxylation, transamination uye kucheneswa kweamino acids. Mukushanda kwezvinhu zvinokonzerwa nehupenyu hwechimiro nehuyu, tripeptide (glutathione) uye murevereri wenheyo yenyika (dinamino-butyric acid) inoumbwa. Glutamic acid iri kuve yakakurumbira mazuva ano. Inowanikwa nenzira yezvokudya zvinowedzera, mishonga, ndeye chikamu chemasanganiswa emitambo yekudya.

Nhengo yehupenyu ye glutamate inobatanidza nekubatanidzwa kwe nitrogen metabolism, kushandiswa kwemamwe amino acids, biosynthesis yemakhahydrates, uye neutralization ya ammonia. Uyewo iyi bio-compound inotora chikamu chekuita mukugadzirwa kwevhitamini B, enzyme yekirasi yei oxidoreductases, nucleotides, muhutano hwe cyclic AMP (adenosine monophosphate acid), HMF (guanosine monophosphate acid), inoratidza basa reurourotransmitter. Glutamic acid inogona kuwedzera kupora kwemyocytes ku ion potassium. Kusvika iye zvino, zvakaratidzwa kuti arginine uye histidine inogona kugadzirwa kubva ku glutamate. Iyo yekupedzisira inobatanidzwa mukushandura kwemagetsi (synthesis of dipeptides of anserine, carnosine). Carnosine inorwisa antioxidant inobatsira kugadzirisa zvirwere zvemasumbu. Anserin inoratidza chiito chakafanana. Mukuwedzera, histidine inobatsira motokari inoshanda mumatumbo, inogadzirisa basa rinoita rechiropa, inowedzera kuvhara gastric, iyo inobatsira pakugadzikana kwekudya kwegomba rekudya.

Panguva yekuwedzerwa kweammonia molecule ku glutamic acid, glutamine inoumbwa. Saka, kune detoxification yeammonia mumuviri. Glutamic acid mumitambo inoshandiswa kugadzirisa kuneta. Maitiro makuru emudzvinyiriri uyu anogona kukunda kusuruvara kwemasisipo nekuda kwekushandisa zvakakwana kwe lactate uye ammonia detoxification. Glutamate inobata anabolic inopindirana nehutachiva hwemumakumbo uye maronda emasumbu. Glucose uye glutamate zvinoshandiswa neuropi sechinhu chinopa simba.

Sezvo sodium inyu ye glutamic acid inofarira nyama, iyi biocompound inowanzoshandiswa sekuwedzera kwezvokudya. Parizvino, glutamate ye sodium inowedzerwa kune zvokudya (mumucheka, masukisi, muto makate, chips, crackers, nezvimwewo) munharaunda dzose dzenyika.

Glutamic Acid: Mirayiridzo

Anonzi pharmacological agent anowanika mune mahwendefa (25 mg). Pamberi pacho, chirwere chacho chakanga chagadzirirwa kudhakwa kwakanyanya, muroti wezuva nezuva hauna kudarika 10 gramu. Kwemazuva ano, kuyerwa kwawedzerwa kusvika 25 g pazuva. Mukurapa kwemitambo, muyero wechirwere ndeyepamusoro (kubva pa30 kusvika ku100 g / zuva). Mushonga wacho hauna hutachiona, pane dzimwe nguva kune rutivi rwomugumisiro muhutano hwemagetsi, kuwedzerwa kunakidza, kusuruvara, kurutsira, chirwere uye chirwere. Vatambi vakakwanisa kwazvo vekirasi yepasi rose, pamwe nemapurotini, vanodya zvinopfuura 120 gramu ye glutamic acid pazuva. Zvisinei, mirayiridzo inoratidza kuti chirwere chezuva nezuva chakakodzera hachifaniri kudarika 4 g.

Chirwere ichi chinorayirirwa kurapwa kwekufa, schizophrenia, psychoses dzakasiyana-siyana, nekuora mwoyo, kusuruvara, myopathies, cerebral palsy , nezvimwewo.

Kupindirana kwekugadzwa kwe glutamic acid: chirwere chechiropa, febrile cider, hypersensitivity, leukopenia, anemia, kuwedzera kubatikana, mudumbu ulcer, nephrotic syndrome.