MCV (kuongorora ropa): decoding. MCV: chimiro

Kuverenga nhamba yemasero eerythrocyte, kusarudza mavhareji evhuti kana kuongorora ropa pamwe chete nedzimwe tsvakurudzo zvinoshandiswa kuisa kusiyana kwakasiyana-siyana kwehutachiona hwehutachiona uye zvimwe zvirwere.

Ndeipi masero matsvuku eropa

Maererano nehutano hwemasero matsvuku eropa (masero matsvuku eropa), ayo anowanikwa mumasero eropa -nuclear asingazivikanwi asina maitiro e biconcave, munhu anogona kutonga mamiriro ehutano hwevanhu. Mumasero eerythrocyte, pane kupemha pigment - protein-ine protein inonzi hemoglobin. Basa guru re erythrocytes ndiko kutumirwa kwe okisijeni, iyo inokosha zvikuru pakushanda kwezvikamu zvose mumuviri. Maumbirwo emasero aya anokonzera mutsvuku wemapfupa. Izvi zvinokurudzirwa ne erythropoietin, iyo inobudiswa muhuwandu hwakawanda neinso masero pasi pemamiriro ezvinhu e hypoxia.

Kazhinji hemoglobin pamwe nekuumbwa kwemasero matsvuku eropa zvinokwanisika chete pamberi pe cyanocobalamin uye folic acid, pamwe nekudya zvakakwana kweyimbi yeoni. Muchidimbu chemagetsi, erythrocytes iripo anenge mwedzi mina. Zvadaro kuparadzwa kwemasero eropa kunoitika, nzvimbo yekuparara kwavo ndeye spleen uye reticulo-endothelial system.

Chii chinonzi MCV?

Nhamba yeCMV ndiyo yerthrocyte index iyo inofananidzira zvinoreva red cell cell volume. Kuti agadzirise kuongororwa kwakajeka kwechirwere, vanachiremba vanogara vachirondedzera chirwere chekuongorora ropa. Kugadzirisa MCV kunotaura nezvemaitiro eropa mumumuviri womunhu. Muvanhu vane hutano, chiyero che erythrocytes kusvika kuhuwandu hwehuwandu hweropa chinogara chiripo, zvinoreva kuti hukuru hwavo uye huwandu hwavo hazvifaniri kuchinja.

Pakukudzika kwehutachiona, kuvhiringidza zvirongwa, kushaya mavhithamini nemaminerari zvinogona kuwanikwa nokuisa MCV-kuongorora ropa. Kududzirwa kwemigumisiro yaro, kuratidzira kukanganisa kubva pachimiro, kunoratidza kuti zvinogona kuitika sei.

Ichi chiratidzo chinotsanangurwa zvose munguva yekliniki yekuongororwa kweropa, uye muchimiro chekudzidza zvakasiyana.

Nzira yekuverenga MCV

Kuti uverenge mavhareji emvura ye erythrocyte, zvakakosha kuparadzanisa sumhi yemasero akawanda muhuwandu hweeerythrocyte masero eropa. Imwe nzira yekuverenga inobva pakuparadzanisa index ye hematocrit kana nhamba ye 1 mm ³ yeropa nenhamba yese masero matsvuku eropa. A hematocrit inoreva kuwandisa kwepakati pakati pehuwandu hwemasero eropa uye kuwanda kweropa.

Pamusoro peCVV, kuongororwa kweropa, kududzirwa kwaro kwakabatana nekuongororwa kwehukuru hwemasero matsvuku eropa, inonzi yakarurama kudarika dzimwe nzira mbiri dzekuverenga. Izvi zvinokonzerwa nekuti apo iyo yakareba ye erythrocyte seki inoshandiswa ne5%, izwi racho rinochinja ne15%. Kuvimbika kwechiratidzo ichi kunogona kushandiswa kana pane nhamba yakawanda yeyerythrocytes iyo inenge yakashandurwa. Semuenzaniso, kana iwe ukaita kuongororwa kweropa, kukosha kweMCV kuchave kwakajeka kana murwere ane zvose macro- uye microcytosis.

Inofanira kutarirwa mupfungwa kuti mum microspherocites iyo yakawanda inowanzoderedzwa, asi muvhareji wevhesi iri mukati mehutano hwakanaka, ndicho chikonzero microscopy yeropa smear inogara ichikurudzirwa.

Unit of measure

Nokuti chiyero chekuyera kwezvinoreva erythrocyte volume (MCV), femtoliters (fl) kana cubic micrometer (μm ³ ) inogamuchirwa.

Chii chinoratidzirwa?

Nekubatsira kwechiratidzo ichi cheropa, marudzi akasiyana-siyana ekushaya ropa anoda kurapwa kwakanaka anowanikwa.

Migumisiro MCV mukuongorora ropa kunogona kusiyanisa:

• Microcytic anemia nekushayikwa kwematare esimbi uye thalassemia, apo kushandiswa kweketeni ye polypeptide, iyo iri chikamu chehemoglobin, inoderera;
• Normocytic kana normochromic anemia, iyo inowedzera muzvirwere zvisingaperi, ine kukanganisa kwemapfupa ekutanga, nemhaka yekuderera kwekugadzirwa kwe erythropoietin;
• Macrocytic anemia nekushayikwa kwe cyanocobalamin uye folic acid, apo kuwanda kwemasero matsvuku eropa kuwedzera.

Hurumende imwe neimwe inoda nzira dzokurapa. Kugadzirisa kuongororwa kunonyanya kukosha kliniki yekuongorora ropa, kududzirwa kweMCV (kureva erythrocyte volume) kunokubvumira kutonga mamiriro emasero matsvuku eropa.

Kana chiratidzo ichi chiine tsika dzakanaka, masero matsvuku eropa anonzi normocytes. Apo migumisiro yerondedzero ye MCV isingatariswi, masero eropa anonzi microcytial, uye kana ari overestimated, anonzi macro-cytoplasmic.

Sarudza kutyorwa kwemvura-electrolyte equilibri mumuviri kunobvumira MCV-kuongorora ropa, kududzirwa kwahwo kunoratidza kuchinja munyuro yemunyu. Kana muvhareji wevhesi yemasero matsvuku eropa ari pasi pezvakaberekwa, unogona kutaura pamusoro pokushayikwa kwemvura mumutumbi wemunhu. Semuenzaniso, nekushaya simba kwehutachiona hwehu hypertonic, MCV mukuyera ropa inoderedzwa. Kana chiratidzo ichi chiri pamusoro pezvakagadzirwa, saka tinogona kutaura pamusoro pekushaya mvura mumvura hypotonic.

Migumisiro yechirongwa cheCVV inogona kushandiswa nezvikonzero zvakasiyana-siyana. Kugadziriswa kwezvinoreva erythrocyte ivhu kunogona kukonzera nzira ye mechanical hemolysis kana kutungamirira chepfu. Low MCV-kuongorora ropa, kududzirwa kunoratidzira kudhakwa kwechiremba uye kushandiswa kwemethanol senhengo inouraya, zvakare hazvisi zvisizvo.

MCV mizinga

Chiratidzo chezvinoreva erythrocyte ivhu chinoenderana nezera remurwere anopfuura kuongorora kweAVV. Chimiro chezera rega rega richave rega, uye rinoratidzwa muchikadzi. Iko mitemo inotarisa huwandu hwechiratidzo ichi, kubva pa80 kusvika ku100 vakadzi vevarwere vakuru.

Muzviitiko zvakawanda, kukosha kweMDCV-kuongorora ropa, kuongorora. Chimiro chakakwirira pane vana vasati vaberekwa. Haifaniri kudarika 140 vakadzikadzi. Sezvo mwana ari kukura, tsika dzakanaka dzechiratidzo ichi dzinoderera. Saka, kune mwana ane gore rimwe chete iyo inowanzove iri pakati pevarume makumi mapfumbamwe nemakumi mana nemakumi mana. Kubva pagore rimwe kusvika pamakore mashanu, kureva kurema kwemasero matsvuku eropa kunopararira kubva kune makumi manomwe kusvika ku85 vakadzikadzi. Kutanga kubva pamakore mashanu uye kusvika kumakore gumi nemigumisiro inowanzoitwa MCV kuongororwa kwe75 kusvika 87 yevakadzikadzi, uye chete nezera rehuwandu huno chiratidzo chinosvika pachimiro chemunhu mukuru.

Underestimation ye MCV

Kana hutachiona hweMVV muhutachiwana huchideredzwa, izvi zvinoratidza kukura kwe microcytic anemia. Iyo inokura apo pane urombo hwematare esimbi muropa remazi, kuvapo kwezvirwere zvisingaperi uye zvirwere zvoupenyu, kukura kwezviremara zvinouraya, kutungamirira chepfu, kuwedzerwa kwemimwe mishonga, kunwa doro zvisina kufanira, uye thalassemia, apo kubatanidza kweketeni ye polypeptide iyo inoita hemoglobin structure inoderera.

Overpriced MCV

Kuwedzerwa kunoreva maitiro emasero eerythrocyte kunoratidza kukura kwe macrocytic anemia nezvimwe zvirwere zvinokonzerwa ne:

• Kushaikwa kweB12 vitamini (cyanocobalamin) kana isina kukwana;
• Kurasikirwa nekushaya simba anemia nekushaiwa folic acid;
• Megaloblastic anemia, inokonzerwa nokuputsa kwehuwandu hweDNA molecules;
• Malignant anemia;
• Hypothyroidism, umo mune kushaya kwehomoni yehomoni;
• Zvirwere zvemukati;
• Zvirwere zvechiropa;
• Kuderedza basa repancreatic cell;
• Zvirwere zvebvu tsvuku yemuseve;
• Kutyisa kana kupisa zvinodhaka;
• Kunwa doro.

Kuongororwa kweAVV kunogona kunge kwakanyanya kudarika zvinowanzoitika apo vakadzi vanotora mishonga yekudzivirira vana. Kusvuta fodya kunogonawo kukonzera kuwedzera mumavhareji masero emasero matsvuku eropa.

Pfungwa ye MCH

Pamwe pamwe netsanangudzo yeCVV, kuongorora kwekuita ropa kunobvumira kusarudzwa kwekutsanangurira kutarisa rudzi rwekushaya ropa. Zvinoreva chiratidzo ichi, vangani pavhareji mune imwe erythrocyte Ino ine iron-ine hemoglobin protein. Inoyerwa mu absolute unit.

Ivhareji inokosha ye hemoglobin inowanikwa mune rimwe erythrocyte inorongwa nokuparadzanisa kuwanda kwehemoglobin nehuwandu hwemasero eerythrocyte. Mukuenzanisa nemutsetse wepavara, MCH-kuongorora inobvumira kunyatsorondedzera huwandu hweprotein yeine iron mune masero matsvuku eropa.

Zvichipa kukosha kweiyo index, anemia inosiyaniswa ne hyper-, hypo- uye normochromic. Normochromia inogona kuwanika kune vanhu vane utano, asi dzimwe nguva inofambisa hemolytic uye aplastic anemia, pamwe nemamiriro ezvinhu anokonzerwa neropa rakanyanya kurasikirwa.

Ne hypochromia, kune kuora kwe erythrocyte volume, inonzi microcytosis, kana kuderera muzvinyorwa zve hemoglobin protein mu erythrocytes ine ruremu rwevhesi. Nokudaro, kusanganiswa kwe hypochromia nezvose zvakaderedzwa ukuru kweyerythrocytes uye normo- uye macro-cytopidha inogoneka.

Kuratidzwa kwehupachiromia kunoitika pasinei nekuzara kwemasero eerythrocyte ane hemoglobin protein uye inokonzerwa chete nemafuta emasero matsvuku eropa. Izvi zvinokonzerwa nekuti sezvo simba re hemoglobine rinowedzera pamusoro pemaitiro ehupenyu, kristalllization uye hemolysis yemasero matsvuku eropa anoitika.